Seattle Seahawks at San Francisco 49ers: Predictions, picks and odds for NFL Week 11 game

Seattle Seahawks at San Francisco 49ers: Predictions, picks and odds for NFL Week 11 game

November 13, 2024

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The San Francisco 49ers (5-4) are getting healthy, and that may be bad news for the NFL. The Seattle Seahawks (4-5) are hoping that doesn’t mean trouble for them when they meet in Northern California in Week 11.

Seattle is coming off a bye and it may have happened at the right time; it is coming off two straight tough home losses and the Seahawks have lost five of their last six games. Plus, the team has missed star receiver DK Metcalf the past two games due to an MCL strain. But with a week off, Seattle has a chance to flip the page and start a strong surge toward the second half of the season.

Christian McCaffrey is back, and the 49ers clearly missed him. The star running back had a solid return and San Francisco overcame some missed field goals to beat the Tampa Bay Buccaneers. It’s the first two-game win streak for the 49ers this season and could be the start of the rebuild to get back in Super Bowl contention.

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49ers vs. Seahawks odds, moneyline, over/under

The 49ers are favorites to defeat the Seahawks, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

  • Spread: 49ers (-6.5)
  • Moneyline: 49ers (-300); Seahawks (+240)
  • Over/under: 50.5

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NFL Week 11 odds, predictions and picks

Eagles vs. Commanders | Bears vs. Packers | Lions vs. Jaguars | Dolphins vs. Raiders | Patriots vs. Rams | Saints vs. Browns | Steelers vs. Ravens | Titans vs. Vikings | Jets vs. Colts | Broncos vs. Falcons | 49ers vs. Seahawks | Bills vs. Chiefs | Chargers vs. Bengals | Cowboys vs. Texans

Lorenzo Reyes: 49ers 29, Seahawks 20

Getting Christian McCaffrey back was huge for San Francisco’s offense, and the return should be even better the more he settles in. The question all season has been about the Niners’ defense, but the group is slowly getting healthier. Seattle, although coming off a bye, struggles to sustain possessions and often has difficulties putting up points.

Tyler Dragon: 49ers 28, Seahawks 20

Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the field. San Francisco’s won three of its last four, including a victory on the road in Seattle. Expect a strong November and December from the 49ers as they eye another postseason run.

Richard Morin: 49ers 23, Seahawks 18

Some look at fighting between teammates as a sign of dysfunction. What it actually shows is passion and a general feeling of wanting to perform better. In other words, it can be a good thing. Give me San Francisco, although I’m skeptical about the 6.5-point spread.

Jordan Mendoza: 49ers 31, Seahawks 26

San Francisco is starting to look like the team expected to return to the Super Bowl. The 49ers have won six straight against the Seahawks, and with Seattle struggling, San Francisco wins again as Christian McCaffrey gets in the endzone.

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