NFL Week 4 odds: Moneylines, point spreads, over/under

NFL Week 4 odds: Moneylines, point spreads, over/under

September 25, 2024

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This NFL season has been downright wacky and unpredictable. In fact, it’s been so unpredictable that it actually made history. In each of the first three weeks, the weekend’s biggest underdogs – New England Patriots in Week 1, Las Vegas Raiders in Week 2, and Washington Commanders in Week 3 – all won outright. That’s never happened in NFL history before.

In Week 4, the title of biggest underdog falls to the Patriots yet again, taking on the San Francisco 49ers. Both teams have a 1-2 record, and San Francisco will be without several of their top stars. Perhaps a fourth massive upset could be in the books?

Here is a collection of our experts’ predictions for each Week 4 contest, plus BetMGM odds for every game.

PROP TALK: These are the best prop bets for NFL games this week 

NFL Week 4 picks/predictions

NFL Week 4 point spreads

  • Dallas Cowboys (-5.5) at New York Giants
  • New Orleans Saints (+1.5) at Atlanta Falcons
  • Cincinnati Bengals (-4.5) at Carolina Panthers
  • Los Angeles Rams (+3) at Chicago Bears
  • Minnesota Vikings (+2.5) at Green Bay Packers
  • Jacksonville Jaguars (+7) at Houston Texans
  • Pittsburgh Steelers (-1.5) at Indianapolis Colts
  • Denver Broncos (+7.5) at New York Jets
  • Philadelphia Eagles (-2.5) at Tampa Bay Buccaneers
  • Washington Commanders (+3.5) at Arizona Cardinals
  • New England Patriots (+10) at San Francisco 49ers
  • Kansas City Chiefs (-8.5) at Los Angeles Chargers
  • Cleveland Browns (+1) at Las Vegas Raiders
  • Buffalo Bills (+2.5) at Baltimore Ravens
  • Tennessee Titans (-1.5) at Miami Dolphins
  • Seattle Seahawks (+3.5) at Detroit Lions

NFL Week 4 moneylines

  • Dallas Cowboys (-250) at New York Giants (+200)
  • New Orleans Saints (+105) at Atlanta Falcons (-125)
  • Cincinnati Bengals (-225) at Carolina Panthers (+180)
  • Los Angeles Rams (+125) at Chicago Bears (-145)
  • Minnesota Vikings (+110) at Green Bay Packers (-135)
  • Jacksonville Jaguars (+260) at Houston Texans (-350)
  • Pittsburgh Steelers (-125) at Indianapolis Colts (+105)
  • Denver Broncos (+280) at New York Jets (-350)
  • Philadelphia Eagles (-145) at Tampa Bay Buccaneers (+120)
  • Washington Commanders (+145) at Arizona Cardinals (-175)
  • New England Patriots (+400) at San Francisco 49ers (-550)
  • Kansas City Chiefs (-400) at Los Angeles Chargers (+325)
  • Cleveland Browns (-105) at Las Vegas Raiders (-115)
  • Buffalo Bills (+115) at Baltimore Ravens (-140)
  • Tennessee Titans (-110) at Miami Dolphins (-110)
  • Seattle Seahawks (+155) at Detroit Lions (-190)

NFL Week 4 over/under

  • Dallas Cowboys at New York Giants: 45
  • New Orleans Saints at Atlanta Falcons: 42.5
  • Cincinnati Bengals at Carolina Panthers: 48
  • Los Angeles Rams at Chicago Bears: 41
  • Minnesota Vikings at Green Bay Packers: 43.5
  • Jacksonville Jaguars at Houston Texans: 45
  • Pittsburgh Steelers at Indianapolis Colts: 40
  • Denver Broncos at New York Jets: 38.5
  • Philadelphia Eagles at Tampa Bay Buccaneers: 45
  • Washington Commanders at Arizona Cardinals: 50.5
  • New England Patriots at San Francisco 49ers: 39.5
  • Kansas City Chiefs at Los Angeles Chargers: 39
  • Cleveland Browns at Las Vegas Raiders: 37
  • Buffalo Bills at Baltimore Ravens: 46.5
  • Tennessee Titans at Miami Dolphins: 37
  • Seattle Seahawks at Detroit Lions: 47