Los Angeles Rams at Detroit Lions: Predictions, picks and odds for NFL Week 1 game

Los Angeles Rams at Detroit Lions: Predictions, picks and odds for NFL Week 1 game

September 4, 2024

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Some think the Detroit Lions (0-0) could be Super Bowl-bound this season. That’s certainly something the Los Angeles Rams (0-0) know a thing or two about, and the 2021 champions will be looking to put an early dent in the Lions‘ campaign to start the season.

While the Lions have been on the come-up over the last few years, the Rams have embarked on a retooling project in wake of their Super Bowl triumph. Are the Rams ready to contend for a championship again, or are there still too many question marks on their roster?

And do the Lions really have what it takes to win it all? The world will be watching in prime time in hopes of an answer to come out of this rematch from last year’s NFC wild-card round.

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Rams vs. Lions odds, moneyline, over/under

The Lions are favorites to defeat the Rams, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

  • Spread: Lions (-3.5)
  • Moneyline: Lions (-175); Rams (+145)
  • Over/under: 51

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NFL Week 1 odds, predictions and picks

Ravens vs. Chiefs | Packers vs. Eagles | Jaguars vs. Dolphins | Steelers vs. Falcons | Vikings vs. Giants | Panthers vs. Saints | Patriots vs. Bengals | Titans vs. Bears | Cardinals vs. Bills | Texans vs. Colts | Raiders vs. Chargers | Broncos vs. Seahawks | Commanders vs. Buccaneers | Cowboys vs. Browns | Rams vs. Lions | Jets vs. 49ers

Lorenzo Reyes: Lions 32, Rams 22

The Rams were a bit of a surprise last season, but I am expecting the Lions to come out focused after a tough loss in the NFC title game. Coach Dan Campbell has stressed that this team is no longer a fun story, but one expected to win. Detroit has the better roster.

Tyler Dragon: Lions 28, Rams 23

Matthew Stafford makes a return trip to the Motor City in a rematch of the 2023 NFC Wild-Card game. Jared Goff got revenge against his former team when he ended the Rams season last year. This season, Goff and the Lions will hand the Rams a Week 1 loss. Detroit is a legitimate contender in the NFC.

Safid Deen: Lions 27, Rams 23

This game will end just like the last one did: With Detroit winning and spoiling Matt Stafford’s return. The Lions are stacked on both sides of the ball, and begin the season with a win.

Richard Morin: Lions 31, Rams 13

The over/under of 51 points could be a tall order given the Rams’ woes on their offensive line. I doubt the Lions will have trouble doing their part, which is why I like Detroit and the points in this matchup.

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