Lions vs. 49ers live updates: How to watch, picks for Monday Night Football in Week 17

Lions vs. 49ers live updates: How to watch, picks for Monday Night Football in Week 17

December 30, 2024

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The 2024 regular season finale of “Monday Night Football” is about as meaningless as a “MNF” matchup can get, but the Detroit Lions and San Francisco 49ers meet in a playoff rematch with revenge on the line.

The 49ers are playing for pride during the last two weeks of the season after being eliminated from playoff contention, a sour end to a disappointing, injury-riddled season. The defending NFC champions downed the Lions in last year’s NFC championship game, but they won’t have an opportunity to meet them in the postseason again.

Meanwhile, the pride of Detroit is the Lions, and they’re roaring en route to the playoffs. Detroit has the inside track to the No. 1 overall seed in the NFC, which they can secure in Week 18 with a win over the Minnesota Vikings, regardless of whatever happens tonight vs. the 49ers.

That said, it might not be a given for a once sure thing of the Lions, who are dealing with multiple injuries at the wrong time, especially on the defensive side of the ball. That could spell trouble for the Lions in Week 17 and beyond.

USA TODAY Sports will provide live updates, highlights and more from the Lions-49ers matchup on “Monday Night Football” in Week 17.

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  • Start time: 8:15 p.m. (5:15 p.m. PT)

The 49ers vs. Lions matchup kicks off at 8:15 p.m. (5:15 p.m. PT).

ESPN again is the broadcast home of “Monday Night Football.” The longtime team of Joe Buck (play-by-play) and Troy Aikman (color) will be on the call, with Lisa Salters adding reports from the sideline.

There will be no “ManningCast” for tonight’s broadcast.

  • Live stream:Fubo  | ESPN+ 

For cord cutters looking for a live stream for the matchup, you can turn to Fubo. Fubo carries NBC, as well as CBS, FOX, NFL Network and the ESPN family of networks, meaning you can catch NFL action through the remainder of the season. 

ESPN+, the proprietary streaming service of ESPN, will also carry the game. 

Here’s how the USA TODAY Sports staff feels the 49ers vs. Lions “MNF” matchup will go down:

  • Lorenzo Reyes: Lions 26, 49ers 16
  • Tyler Dragon: Lions 28, 49ers 20
  • Richard Morin: Lions 31, 49ers 20
  • Jordan Mendoza: Lions 28, 49ers 20

The Lions are favorites to defeat the 49ers, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks and best bets for every NFL game this week. 

  • Spread: Lions (-3.5) 
  • Moneyline: Lions (-210); 49ers (+170) 
  • Over/under: 50

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