Indianapolis Colts at Green Bay Packers: Predictions and latest odds for NFL Week 2

Indianapolis Colts at Green Bay Packers: Predictions and latest odds for NFL Week 2

September 14, 2024

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Two teams seeking a first win of this new NFL season meet Sunday, as the Green Bay Packers and Indianapolis Colts collide in Week 2 at Lambeau Field.

The Packers suffered a 34-29 loss to the Philadelphia Eagles in an opener played in Brazil, and the news was much worse than simply starting off 0-1. Quarterback Jordan Love suffered a knee injury the team said was an MCL sprain, and is listed as questionable to play. Making matters worse, lead running back Josh Jacobs is also questionable after being a limited participant in practice.

The Colts, meanwhile, traded points with the Houston Texans all game long only to come up short in a 29-27 home loss. Wide receiver Alec Pierce had a good day at the office, posting 125 yards and a touchdown, but QB Anthony Richardson ended up with a dubious 9-for-19 line on the stat sheet. A bigger issue? Finishing drives out on defense, with Indianapolis giving up over 400 total yards and 26 first downs in that season-opening defeat.

NFL Week 2 injury report: Christian McCaffrey ruled out

Colts vs. Packers odds, moneyline, over/under

Despite being on the road, the Colts are favored to win on Sunday, per BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

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  • Spread: Colts (-3)
  • Moneyline: Colts (-145), Packers (+120)
  • Over/under: 40.5 points

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NFL Week 2 odds, predictions and picks

USA TODAY: Colts 24, Packers 17

Tyler Dragon writes: “I would’ve picked the Packers in this game before the year. But Green Bay’s season took a turn for the worse once Jordan Love went down in the final seconds of the team’s Week 1 loss. Malik Willis has a chance to revitalize his career in the next few weeks while Love is out. However, Anthony Richardson and the Colts will get their first victory of the season Sunday.”

CBS Sports: Colts 23, Packers 20

Pete Prisco writes: “This will be Malik Willis for the Packers with Jordan Love out. That’s a real challenge for Matt LaFleur and the coaching staff. The Colts hit some big plays on offense against the Texans, but gave up a bunch. The Packers will rally around their new quarterback, but it won’t be enough. Colts get a road victory.”

The 33rd Team: Packers 23, Colts 20

Marcus Mosher writes: “This might be the toughest game of the week to predict with Jordan Love (MCL) out and Malik Willis in the starting lineup for the Green Bay Packers. The good thing for the Packers is they have a few extra days to get Willis ready after playing on Friday night in Week 1. However, expect a much more conservative game plan and more work for Josh Jacobs. The Indianapolis Colts will follow a similar game plan but with several deep shots down the field from Anthony Richardson. The Colts are favored, but we are taking the Packers to pull off the upset at home in Lambeau this week.”

Bleacher Report: Colts 23, Packers 17

Brent Sobleski writes: “This battle between Indianapolis and Green Bay is slanted in the Colts’ favor based on the hits taken at different premium positions. Jordan Love won’t play for at least a few weeks after suffering an MCL sprain in Week 1… Expect the Colts to load the box against the run and play better in that area than they did against the Texans.”