Buffalo Bills at Los Angeles Rams: Predictions, picks and odds for NFL Week 14 game

Buffalo Bills at Los Angeles Rams: Predictions, picks and odds for NFL Week 14 game

December 4, 2024

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The Buffalo Bills look to complete a clean sweep of the NFC West this weekend as they take on the Los Angeles Rams. The Bills took care of business a week ago, destroying the San Francisco 49ers in the snow at Highmark Stadium. Now, they’ll go on the road to take on a more formidable Rams‘ teams that has teeter-tottered between demonstrating a tremendous offense and being one of the most mediocre teams in the NFL.

We know the damage that Cooper Kupp and Puka Nacua can do, but we haven’t had a game recently where both have taken control like we’ve seen many times before. It likely won’t happen against a stout Buffalo Bills defense this weekend, but crazier things have happened, and the Rams are in desperate need of every win they can get at this point, sitting one game back in the NFC West.

Here are our experts’ predictions for this Week 14 showdown.

Rams vs. Bills odds, moneyline, over/under

The Bills are favorites to defeat the Rams, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks and best bets for every NFL game this week.

  • Spread: Bills (-4.5)
  • Moneyline: Bills (-225); Rams (+185)
  • Over/under: 49

NFL Week 14 odds, predictions and picks

Lions vs. Packers | Dolphins vs. Jets | Vikings vs. Falcons | Giants vs. Saints | Eagles vs. Panthers | Steelers vs. Browns | Buccaneers vs. Raiders | Titans vs. Jaguars | Cardinals vs. Seahawks | Rams vs. Bills | 49ers vs. Bears | Chiefs vs. Chargers | Cowboys vs. Bengals

Lorenzo Reyes: Bills 30, Rams 20

Buffalo is one of those teams you should back pretty much the rest of the way, with the possible exception being Week 15 at Detroit. The Rams are inconsistent, and the Bills have found a steady rhythm on both sides of the ball.

Tyler Dragon: Bills 30, Rams 22

Buffalo is playing like the best team in the AFC. They are still in contention for the No. 1 seed in the conference. This is a measuring-stick game for the Rams. But I don’t think they’ll measure up against the Bills.

Richard Morin: Rams 30, Bills 28

The Rams have quietly become a serious postseason contender. I’m picking them to upset the Bills in Inglewood.

Jordan Mendoza: Bills 30, Rams 27

Buffalo is proving to be a tough team to beat, but Los Angeles’ offense has the potential to match anything the Bills do. While the Rams put the pressure on the Bills, Josh Allen finds a way to keep the winning streak alive.