Arizona Cardinals at Seattle Seahawks: Predictions, picks and odds for NFL Week 12 game

Arizona Cardinals at Seattle Seahawks: Predictions, picks and odds for NFL Week 12 game

November 20, 2024

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With the entirety of the NFC West within one game of each other, the division is anyone’s race. That makes this matchup between the Seattle Seahawks and Arizona Cardinals all the more pivotal.

A loss for Seattle would put them at 5-6, two games out of first place with a 1-3 record in divisional play. That’s a death sentence for anyone looking to reach the playoffs. Arizona, meanwhile, has a little more leeway. They’ve yet to lose in the division, and they are coming off a bye. They’ll be well-rested and well-prepared for this matchup.

Here are our experts’ predictions for this Week 12 NFC West showdown.

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The Cardinals are favorites to defeat the Seahawks, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

  • Spread: Cardinals (-1)
  • Moneyline: Cardinals (-110); Seahawks (-110)
  • Over/under: 47.5

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NFL Week 12 odds, predictions and picks

Browns vs. Steelers | Panthers vs. Chiefs | Bears vs. Vikings | Texans vs. Titans | Colts vs. Lions | Dolphins vs. Patriots | Giants vs. Buccaneers | Commanders vs. Cowboys | Raiders vs. Broncos | Packers vs. 49ers | Seahawks vs. Cardinals | Rams vs. Eagles | Chargers vs. Ravens

Lorenzo Reyes: Cardinals 27, Seahawks 23

Arizona is coming off its bye and Kyler Murray has been excellent this year. The Seahawks and coach Mike Macdonald have installed an oppressive defense, but I’m more concerned about Seattle’s offense keeping pace with the Cardinals.

Tyler Dragon: Seahawks 24, Cardinals 22

This one has the potential to be the game of the week. Kyler Murray and the Cardinals have been a pleasant surprise this year. However, the Seahawks got a massive win in San Francisco last week. A home victory versus Arizona could put them in the driver’s seat in the NFC West. 

Richard Morin: Seahawks 21, Cardinals 20

The NFC West gets even more jumbled as the Seahawks and Cardinals both move to 6-5 after this one.

Jordan Mendoza: Cardinals 23, Seahawks 20

This game will be the true test of whether the Cardinals are a legit playoff contender. Kyler Murray provides some more magic to give Arizona a remarkable fifth-straight win.

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(This story was updated to change a video.)