Cardinals at Rams: Predictions, picks, odds for NFL Week 17 game

Cardinals at Rams: Predictions, picks, odds for NFL Week 17 game

December 25, 2024

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It’s an NFC West showdown in Week 17 that could drastically change the landscape of the division. The Los Angeles Rams, after a 1-4 start to the season, have won eight of their last ten, but this upcoming matchup against the Arizona Cardinals could put a halt to their hot streak.

After all, the first time these teams played in Week 2, the Cardinals won 41-10. However, the Rams have improved drastically since then. Wide receiver Puka Nacua was unavailable for that game, and fellow wideout Cooper Kupp got injured early on. Perhaps their presence, combined with the confidence of a team that has won a lot lately, will give the Rams the edge at home.

Here are our experts’ predictions for this NFC West matchup.

Rams vs. Cardinals odds, moneyline, over/under

The Rams are favorites to defeat the Cardinals, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks and best bets for every NFL game this week.

  • Spread: Rams (-6.5)
  • Moneyline: Rams (-275); Cardinals (+225)
  • Over/under: 48

NFL Week 17 odds, predictions and picks

Steelers vs. Chiefs | Texans vs. Ravens | Bears vs. Seahawks | Patriots vs. Chargers | Bengals vs. Broncos | Rams vs. Cardinals | Bills vs. Jets | Jaguars vs. Titans | Saints vs. Raiders | Buccaneers vs. Panthers | Eagles vs. Cowboys | Giants vs. Colts | Browns vs. Dolphins | Vikings vs. Packers | Commanders vs. Falcons | 49ers vs. Lions

Lorenzo Reyes: Rams 23, Cardinals 17

The Rams have been red hot lately, are in first in the NFC West and the Cardinals are eliminated from playoff contention. I think L.A. takes care of business.

Tyler Dragon: Rams 27, Cardinals 20

The Rams are on the cusp of an NFC West title after a 1-4 start. They are playing some of the best football in the NFL. The Cardinals are already eliminated from the postseason.

Richard Morin: Rams 30, Cardinals 13

The Cardinals have to be licking their wounds after a loss to Carolina. The Rams, meanwhile, are sneakily playing great football.

Jordan Mendoza: Rams 30, Cardinals 20

Los Angeles has truly turned its season around in stunning fashion. Los Angeles inches toward clinching the division with an impressive performance against Arizona.