49ers at Dolphins: Predictions, picks, odds for NFL Week 16 game

Admin December 18, 2024

It’s been a disappointing season for both the San Francisco 49ers and Miami Dolphins. Each team came into the year with playoff expectations, but heading into Week 16, both teams have been all but eliminated. Each team’s offense was supposed to be near the top of the league, but they’ve both been middle of the road.

Injuries, regression, and drama have marred each of these team’s seasons, but there’s still something to play for. Both teams are still technically still alive, and until that hope disappears entirely, neither of these teams are going to go down easy.

Here are our experts’ predictions for this Week 16 showdown.

Dolphins vs. 49ers odds, moneyline, over/under

The 49ers are favorites to defeat the Dolphins, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks and best bets for every NFL game this week.

Spread: 49ers (-1)
Moneyline: 49ers (-110); Dolphins (-110)
Over/under: 44.5

NFL Week 16 odds, predictions and picks

Tyler Dragon: Dolphins 25, 49ers 22

Mike McDaniel faces his former team. Hopefully Tua Tagovailoa isn’t a turnover machine in this one. There’s still an outside chance for Miami to make the playoffs. The 49ers are waiting for their Super Bowl 58 hangover to be over at this point.

Jordan Mendoza: Dolphins 25, 49ers 20

Whoever loses, their season is done for. There’s tons of dysfunction going on with the 49ers, and it’s the mistakes that hurt them and come to the benefit of Miami.

(This story was updated to change a video.)