Admin December 11, 2024
The fight for the NFC West is on full display when the Los Angeles Rams visit the San Francisco 49ers on “Thursday Night Football.”
Our USA TODAY Sports experts predicted which team would win this divisional showdown and which would or would not cover the spread. For more information on other games, check out the full list of NFL Week 15 picks against the spread.
Now, let’s check out the Rams vs. 49ers odds:
TNF odds, moneyline, over/under
The 49ers are favorites to defeat the Rams, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks and best bets for every NFL game this week.
- Spread: 49ers (-3)
- Moneyline: 49ers (-155); Rams (+130)
- Over/under: 49.5
Rams vs. 49ers picks against the spread
Lorenzo Reyes: 49ers can cover
While San Francisco cannot catch a break with its injuries, the 49ers played their best game of the season against a very good Bears defense. Isaac Guerendo may have a shot to go, but I think the biggest recent move for the Niners was the return of safety Talanoa Hufanga. ― Prediction: 49ers 28, Rams 23
Tyler Dragon: Rams will pull off upset
This is a huge game for the 49ers as they hope to keep their playoff dreams alive. The Rams have won the past two meetings with San Francisco, and LA is coming off a signature win against the Bills. The Rams will carry momentum from last week into The Bay. ― Prediction: Rams 26, 49ers 21
Richard Morin: 49ers not a safe bet
This is a tough one to pick on the spread, but the Rams have fully hit their stride and are positioned to make a run at the NFC West. ― Prediction: Rams 28, 49ers 27