Los Angeles Chargers at Arizona Cardinals: Predictions, picks and odds for NFL Week 7 game

Los Angeles Chargers at Arizona Cardinals: Predictions, picks and odds for NFL Week 7 game

October 16, 2024

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The Week 7 finale will take place in the desert with the Arizona Cardinals (2-4) hosting the Los Angeles Chargers (3-2) in a special ESPN+ edition of “Monday Night Football.”

Even against a tough defense, the Chargers opened up with a strong start against the Denver Broncos to snap a two-game losing skid. The offense has steadily grown in the first month of the season, but the defense is proving to be among the toughest in the league.

All sorts of things went wrong when Arizona took a visit to Lambeau Field; the Cardinals were dominated in every facet against the Packers. It was a disappointment considering they were coming off a major win against the 49ers, but Arizona can add another big win with a primetime appearance.

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Cardinals vs. Chargers odds, moneyline, over/under

The Chargers are favorites to defeat the Cardinals, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

  • Spread: Chargers (-3)
  • Moneyline: Chargers (-150); Cardinals (+125)
  • Over/under: 44

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NFL Week 7 odds, predictions and picks

Saints vs. Broncos | Jaguars vs. Patriots | Falcons vs. Seahawks | Bills vs. Titans | Browns vs. Bengals | Packers vs. Texans | Colts vs. Dolphins | Vikings vs. Lions | Giants vs. Eagles | Rams vs. Raiders | Commanders vs. Panthers | 49ers vs. Chiefs | Steelers vs. Jets | Buccaneers vs. Ravens | Cardinals vs. Chargers

Lorenzo Reyes: Chargers 29, Cardinals 13

This is a terrible matchup for the Cardinals, who struggle to stop the rush. Not only that, the Chargers have the NFL’s top-scoring defense, and Arizona is likely to be without Marvin Harrison Jr. This line feels like it should be far higher. I love L.A. in this spot.

Tyler Dragon: Chargers 23, Cardinals 21

Both these teams have top-10 rushing offenses. But the Chargers also have a top-10 defense and rank No. 1 in scoring defense. The Chargers have the personnel to be the more dominant team in the trenches. Justin Herbert is coming off his first 200-yard passing game under coach Jim Harbaugh.

Richard Morin: Cardinals 28, Chargers 24

Especially if Marvin Harrison Jr. returns from his concussion, a Cardinals upset could be in the cards on Monday Night Football.

Jordan Mendoza: Chargers 20, Cardinals 16

Los Angeles has shown it doesn’t mind playing − and winning − ugly games. The Chargers defense gives Kyler Murray another tough week to move to 4-2.

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